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10.1093/jn/103.10.1454 [PubMed: 4200872] [CrossRef] Oppermann JA, Muldoon E, Ranney RE (1973b)

Intrathecal administration, while conceptually the most direct way to approach brain iron, is highly invasive and currently studied only in experimental scenariosit may be considered in extreme cases or acute CNS iron toxicosis, but it is not a routine approach due to the safety and logistical challenges

Authors' contributions MR and KK performed the subject identification, clinical evaluations and coordinated the follow-ups of the subjects

Kinetics of the Yeast Cystathionine -Synthase Forward and Reverse Reactions: Continuous Assays and the Equilibrium Constant for the Reaction